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and hence is demonstrated a marked diversity in the mode of action of tobacco on different systemsIt is clear that, if in one individual tobacco is able to produce conditions favorable to a disease [apoplexy (stroke)] which may kill at any moment, and in another is practically inert, it is useless to argue either that is generally highly dangerous, or, on the other hand, destitute of dangerous effects

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This results in a rich tapestry of flavors, including notes of dark chocolate, espresso, and a subtle spiciness that lingers on the palate

It does not aim to replicate nicotine or trick the bodyit replaces the material , not the effect